Understanding of morphine use


Morphine is the only drug in a group of drugs called end-OIL ( Opioid ).

But the drugs in the opioids There are several other types, such as Codeine , Tramal, or Pethidine. In this article, we will use the term “morphine” instead of the opioid pain relievers. Because these drugs have similar effects and morphine is frequently used in this class of drugs. In each country, morphine consumption is measured. Most of which are found in developed countries They have higher morphine usage rates than developing countries. In Thailand, it was found that We use approximately 40 kilograms of morphine per year from the actual amount we should use. Which is about 1,000 kilograms per year.

Questions about morphine
Question: Is the pain of cancer really resolved with morphine?

Answer: Not always.

Fact: It depends on what kind of pain it is and how severe it is. In most cases, doctors will start using weaker drugs, such as paracetamol , NSAIDs used for joint pain, aches, and if these drugs do not go away, they will be treated with painrelief. A small dose of morphine may be started.

Question:  Does eating more morphine mean worsening symptoms?

Answer: Not always.
Fact: It could be from worsening of the disease, or it could be because of the early stages. The doctor first gave the pain medication a small dose and then gradually. Adjust it to the right size. To provide patients with a good quality of life and to live as close as possible to when they were not sick.

Question: Is morphine drug addictive or not?

Answer: Not always.
Fact: Addiction means having to increase the dose more and more. Even if the patient’s condition has not changed and the drug cravings when not taking the drug Morphine has an addictive effect and is therefore addictive. However, if a cancer patient has severe pain and needs more morphine We will not call it an addiction, but a drug use as needed.

Question: Does the use of morphine actually increase the death of the patient from depressed breathing?

A: Wrong.
Truth: Starting a small dose of morphine did not cause respiratory depression and did not cause death in the patient. Respiratory depression in patients is often caused by excessive dosing. In people who have never received morphine before It may happen in the case of miscalculating the drug or starting too much of the drug because the patient is in pain.

Question: Does morphine really cause constipation?

A: Yes
, Truth: Constipation is the most common side effect in patients taking morphine and is a constant side effect during morphine use. Because morphine slows down the intestinal movement Patients taking morphine should take the medicine to prevent constipation. If your doctor doesn’t Don’t forget to ask. Morphine also has other side effects, such as nausea, vomiting, and drowsiness. Taking too much of it can lead to muscle spasms or confusion. Which is a symptom that is found before breathing pressure but often have to eat a lot Or increase in size rapidly.

Question: Does morphine help with shortness of breath in cancer patients?

Answer: Yes
, Truth: Most people understand that morphine primarily relieves pain in cancer patients, but morphine actually helps reduce the symptoms of asthenia in cancer patients whose disease spreads to the lungs, such as watery fluids. Lungs Many patients who choose not to puncture the lungs to reduce their symptoms of asthenia, may choose morphine instead.

Question: Should people with kidney disease really use morphine?

Answer: Wrong.
Truth: morphine can be used by people with kidney disease. But more caution must be exercised because morphine is excreted by the kidneys. Therefore, morphine should be given starting at a small dose, gradually increasing slowly and watching for side effects. But it is not contraindicated to use morphine in patients with kidney disease.

Question: If long-acting morphine is obtained, morphine should not be taken during the day as it may lead to excessive morphine exposure or not?

Answer: Wrong.
Truth: Patients with pain can use small doses of morphine. During the day This typically accounts for 10% of the long-acting morphine dose taken all day. If it is an oral pill, it can be taken every 2-4 hours when the pain occurs. The doctor will actually calculate the amount of medication the patient should receive. On the following day from the daily dose of morphine combined with the long acting morphine.

Question: Oral and injectable morphine works as powerful as Really or not?

Answer: Wrong.
Truth: Injectable morphine is 2-3 times stronger than oral. Therefore, when switching from injectable to oral pills. Don’t forget to increase the size by 2-3 times.

Question: Oral and injectable morphine started working as quickly as possible. Together and act as long as Really or not?

Answer: Wrong.

Truth: Injectable morphine acts faster and loses its effect faster. If administered in a line, it may pass out within 1-2 hours, while oral morphine lasts for 2-4 hours, but long-acting morphine can last up to 12-24 hours.